Endocrine Abstracts

Objective: To evaluate the prognostic value of interleukin-8 studies in the development of thyrotoxic cardiomyopathy in patients with Graves’ disease.Materials and methods: 86 patients with newly diagnosed Graves’ disease were examined, aged 18 to 55 years (mean age 37 years [28; 45]) without previous cardiovascular events. All patients were analyzed by interleukin-8 by immuno-enzyme analysis. To determine the threshold value for Interleukin-8,...

Objective: To assess the quality of life, the presence and severity of depressive symptoms in patients with diabetes combined with gastroparesis and without itMethods: Forty three patients with diabetes were included in the study. The presence and severity of gastrointestinal symptoms, as well as the intensity and frequency of symptoms over the last 2 weeks, were measured with the Patient Assessment of the upper gastrointestinal symptom severity index (P...

Background: Was performed an open study in 2 parallel groups to compare the efficacy and safety of dulaglutide and liraglutide in combination with Metformin in patients with type 2 diabetes mellitus.Methods: Thirty-two patients (13 men and 19 women) with type 2 diabetes mellitus with unsatisfactory glycemic control on Metformin monotherapy were examined. The median age was 52 [44; 61] years old, the duration of diabetes was 4.6 [2,5; 9,0] years, median o...

Proper insulin injection technique is a prerequisite for achieving good diabetes control, reducing absorption variability, and getting the best effect from using the drug. At the same time, the rate of absorption of insulin depends on a number of technical features, which include the depth of needle insertion, the severity of blood flow and the presence of lipodystrophy in the injection zones. Compliance with a number of rules minimizes the variability of absorption of insulin...

Objectives: Estimate the prevalence of of cardiovascular symptoms, to identify the main changes in echocardiography at Graves disease (GD) and their dynamic during treatment.Methods: Investigated 86 patients with GD. The functional class (FC) chronic heart failure (CHF) was determined according to the New York Heart Association (NYHA). All patients underwent echocardiography before treatment and after 3 months of euthyroid state.Re...

The research goal was to study serum concentration of immunoregulatory cytokines (IL-1ß, IL-6ß, IL-8ß, IL-10ß) in 80 patients with manifest hypothyroidism at the age of 21–50. 48 patients suffering from chronic autoimmune hypothyroidism and 32 patients with postoperative hypothyroidism were examined. It was revealed that autoimmune hypothyroidism effects balance disturbance of cytokine-producing activity Th1 and Th2 types, this plays an important role ...

Assess the morphology of focal lesions of the adrenal glands after adrenalectomy, compare the results with the nature of the course of hypertension, the level of blood pressure, age, sex of patients.Materials and methods: Forty-four medical maps of patients operated on for focal formations of the adrenal glands were analyzed. The clinical symptoms, the hormonal activity of adrenal gland tumors - the level of cortisol, aldosterone, potassium, sodium, reni...